Prescription weight care, calibrated to you.
GLP-1 + B12 is one path in a physician-designed program built around your biology, your tolerance, and the pace you actually want to move at.
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GLP-1 + B12
A weekly GLP-1 injection paired with B12 to keep energy steady while appetite settles.
Price reflects the per-month rate billed across the selected term. Final eligibility and dosing are determined by your prescribing physician.
Appearance, dosage and content of the vials might actually be different for each patient based on prescription.
Billed $1,974 every 6 months for one full protocol cycle. Cancel anytime up to 48 hours before an order.
- ↻Subscription: A new order is processed every 6 months. Cancel anytime up to 48 hours before an order.
- 🛡Reassessment: A provider must renew your prescription after 5 refills or after 1 year, whichever comes first.
- ↻Refills: Orders are processed automatically by the pharmacy every 6 months.
- 🗓Order Supply: Each cycle is dispensed as prescribed by your provider for the full 6-month term.
Provider prescribed. Dispensed by a licensed partner pharmacy. Created with care.
Peptonics GLP-1 + B12 is a once-weekly subcutaneous injection that combines a GLP-1 receptor agonist with methylcobalamin (vitamin B12). The GLP-1 component supports satiety, slows gastric emptying, and helps regulate post-meal glucose. The B12 add-in is included to help offset the fatigue and low-energy days some patients describe in the first weeks of a GLP-1 protocol.
Mechanism of action
GLP-1 receptor agonists mimic a hormone your gut already produces after meals. They bind to receptors in the pancreas, brain, and stomach to amplify insulin response, dampen glucagon, and lengthen the time food sits in the stomach. Together, those effects lower hunger cues and stabilize blood sugar between meals. Methylcobalamin is the bioactive form of B12 and supports red-cell formation and cellular energy metabolism — a useful pairing while calorie intake is lower than usual.
Potential benefits
- 01Steady appetite reduction without hour-by-hour cravings
- 02Smoother post-meal glucose and fewer afternoon energy crashes
- 03Supports gradual, sustained weight loss alongside lifestyle changes
- 04B12 helps maintain energy through the early titration weeks
- 05Once-weekly dosing — easy to fit into a routine
Care designed one patient at a time.
No two bodies respond identically. Your protocol shouldn't be identical either — biology, goals and daily life all shape the formula your physician writes.
Dose, additive stack and titration cadence are written for your intake — not pulled off a shelf.
Message your care team between visits. No phone trees, no waiting room, no chasing refills.
Every vial is prepared by a U.S. licensed compounding pharmacy and shipped direct to you.
Check-ins, lifestyle prompts and side-effect support keep the protocol on the rails.
Private member spaces with people running the same protocol — real stories, real pacing.
First shipment includes a starter guide, journal, and anti-nausea support so day one isn't day zero.
Your journey is personal.
Your plan should be too.
Manage your protocol, lab results and refills from a single private dashboard, anywhere.
Secure messaging with the physicians and specialists assigned to your plan, included.
Multi-month protocols are scheduled ahead so there's no scramble when one cycle ends.
Three steps into your next chapter.
Build your formula
Share your goals, history and tolerance through a guided intake. Takes about ten minutes.
Physician-written plan
A state-licensed MD or DO reviews your intake and writes a protocol scoped to you.
Stay on track
Ongoing physician access plus structured check-ins to adjust the protocol as you progress.
Actives & ingredients
- GLP-1 receptor agonist (semaglutide), dose individualized
- Methylcobalamin (active B12) for energy and metabolic support
- Sterile bacteriostatic water as the diluent
Side effects & considerations
The most common early side effects are nausea, mild constipation or loose stools, and reduced appetite — usually most noticeable in the first week of each dose increase and easing as your body adapts. Less commonly: heartburn, fatigue, headache. GLP-1 therapies are not recommended for people with a personal or family history of medullary thyroid carcinoma or MEN2, and are not used in pregnancy. Your physician will review your full history and any current medications before prescribing.
Common questions
The PeptidesQ starter kit.
Your first delivery isn't just a vial. Members receive a welcome packet with a protocol guide, a tracking journal, and supportive add-ons for the first weeks of titration.
- Onboarding guide written for your protocol
- Progress journal for weight, dose and how you feel
- Anti-nausea support for early titration
- Lab requisition where clinically indicated
Ready to start GLP-1 + B12?
Membership is by application. Your protocol is reviewed and adjusted by a licensed physician before it ships.
Apply for membership